Posts about:
Bioanalytical Platforms
Platform Spotlight: ImmunoCAP to Support Diagnosis of Allergic Reactions Against Biologics
Ultimately, all biologicals are immunogenic leading to the formation of anti-drug antibodies (ADA). In most cases, these antibodies are of IgG isotype. In some cases...
Immunogenicity Assessment Using the Biacore™ T200 SPR System
By PD Dr. Arno Kromminga & Dr. Daniel Worms
All therapeutic proteins have the potential to induce an immune response that can lead to the formation of anti-drug...
The Fit for Flow Cytometry, Part 1: Ideal for Receptor Occupancy Assessment
The rise of precision medicine has brought with it unprecedented breakthroughs in biologic drug development, particularly related to immunotherapy. These novel...
Supporting a Gene Therapy Clinical Trial with Assay to Measure NAbs Against the AAV9 Serotype
Gene therapy is experiencing an exciting resurgence with the development of new genome editing tools and new gene delivery vectors. Approximately 60% of gene therapy...
Ligand-Binding Assay Optimization, Part 1: Critical Attributes of Platforms Used
Consistent discussion and improvement upon the standard practices of bioanalytical laboratories is critical to improving the work we do supporting innovative biologics...
ELISA, the Most Used Immunoassay Platform in Large Molecule Bioanalysis
Biologics development is an inherently complex field. In order to carry out the stringent bioanalytical testing your studies require, you not only need expert...