The Difference Between Pharmacokinetics and Pharmacodynamics
If you’re searching for the “difference between pharmacokinetics and pharmacodynamics (PK/PD)” or wondering “what is PK vs PD in drug development,” this article...
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Enabling a Breakthrough in Gene Therapy: A Case Study in Analytical Support for CRISPR-Based Innovation
In March 2025, a landmark moment in gene therapy quietly reshaped what’s possible in the treatment of ultra-rare diseases. A team at Children’s Hospital of Philadelphia (CHOP) successfully administered a personalized CRISPR-based therapy to a young patient diagnosed with a fatal metabolic disorder just days after birth.
Unraveling the Biosimilar Paradox
Demonstrating equivalence in a landscape of evolving technologies and regulations
Riding a wave of blockbuster molecule patent expirations, the global biosimilar market grew to nearly $18 billion in 2020. With a total of 26 blockbuster drugs coming off patent in the next five years, the market is expected to reach $75 billion by 2030.1 Biosimilar developers have an opportunity to capture this growing market, but only if they overcome changes in manufacturing requirements, impacts of next-generation assay sensitivity, and increasing pressures to move quickly. 2
CMC Analytical Control Strategies for Drug Development
An Introduction to CMC
Large Molecule Bioanalysis using LC/MS
Introduction to Large Molecules
LC/MS Applications in Drug Development
Basic Principles of LC/MS Methods
PCR as a Bioanalytical Tool for Gene and Cell Therapy
The third and final blog in our cell and gene therapy series will focus on PCR as a bioanalytical tool for gene and cell therapy. Be sure to read our first blog on bioanalytical support for gene therapy programs and the second blog on the safety and efficacy testing of cell therapies.
Safety and Efficacy Testing of Cell Therapies
An Overview of Cell Therapy:
Bioanalytical Support for Gene Therapy Programs
An Introduction to Gene Therapy:
Receptor Occupancy Flow Cytometry Assays
This is the final blog in our three-part flow cytometry series. Part 1 highlighted the broad application of flow cytometry for bioanalysis, part 2 investigated the use of flow for immunogenicity assessment for cell therapies, and in this third installment we will discuss the application of flow for receptor occupancy.