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Lactose intolerance in IBS patients

Much has been written about the IBS and small intestinal bacterial overgrowth.  Fewer studies have focused on the incidence of lactose intolerance in IBS patient in spite of the fact it is very common for these patient to self perceive that they are lactose intolerant.   A recent study evaluated 51 IBS patients using the hydrogen breath test to ascertain the prevalence of lactose intolerance. A total of 24 of 51 (47%) had a positive hydrogen breath test for lactose intolerance.  Furthermore, the researchers noted that patients with a high severity of IBS were more likely to test positive for lactose intolerance.

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Fructose Malabsorption and IBS

A high prevalence of Fructose malabsorption has been reported in previous studies of IBS patient. This research sought to examine whether the findings held up in a statistically significant number of Indian patients.  The study enrolled 97 patients with confirmed IBS using the Rome III criteria and 41 healthy controls.  Each subject was given a hydrogen breath test for Fructose Malabsorption.  The result was that IBS patients tested positive for fructose malabsorption at a statistically significant rate higher as compared to controls.  Furthermore, patients with diarrhea-predominant IBS had a 91% positive rate for fructose malabsorption as measured by the hydrogen breath test.

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Hydrogen breath test for SIBO and irritable bowel syndrome

The hydrogen breath test shows the bacterial fermentation of unabsorbed intestinal carbohydrates. Malabsorption of carbohydrates is a key trigger of irritable bowel syndrome type symptoms such as diarrhea and/or constipation, bloating, excess flatulence, headaches and lack of energy.  When bacteria is present in the small intestine this bacteria will metabolize the carbohydrates producing the IBS like symptoms.  The authors of this research believe that patients with persistent symptoms of abdominal bloating and distension despite dietary intervention should take a hydrogen breath test to determine if they have small intestinal bacterial overgrowth (SIBO).  A proper diagnosis of SIBO can lead to effective treatment of the condition and relief of the IBS symptoms.

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Link between hypothyroidism and SIBO

Altered small intestinal motility increases the risk of developing small intestinal bacterial overgrowth (SIBO).  Hypothyroidism is known to alter small intestinal motility.  This research conducted in India evaluated the link and found that patients with hypothyroidism have a high propensity to develop SIBO.  The researchers used the hydrogen breath test to detect SIBO.  Fortunately, both antibiotics and probiotics can effectively manage the symptoms of SIBO.

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Leaky gut syndrome and IBS

This article discusses the link between irritable bowel syndrome (IBS) and leaky gut syndrome. The authors state that increased intestinal permeability (leaky gut) has been observed in IBS patients with diarrhea. IBS patients show higher numbers and increased activation of mucosal immunocytes. A potential therapeutic option is to use probiotics. Certain probiotic strains have useful properties including anti-inflammatory effects. Metabolic Solutions offers the sucrose breath test to confirm the presence of leaky gut syndrome.

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Can glutamine be used to detect leaky gut syndrome

Intestinal permeability, also known as leaky gut syndrome, maybe the underlying cause of allergies and intestinal disorders such as irritable bowel syndrome. Researchers at the University of Burgundy France believe that leaky gut syndrome maybe linked to protein and lipid glycation induced by modern food processing. As a result they suggest that dietary supplements such as glutamine and /or curcumin can improve the condition by inhibiting inflammation and oxidative stress. Metabolic Solutions offers the sucrose breath test to assess your intestinal function.

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Lactose Intolerance and IBS

This new research studied patients with diarrhea predominant irritable bowel syndrome. The researchers found that about 50% of these patient tested positive using the hydrogen breath test for lactose intolerance. These patients were also characterized by high levels of anxiety, mucosal activation and increased visceral sensitivity. Interestingly, the researchers found that these patients when treated through dietary modification showed improvement in their symptoms. Thus the researchers concluded that a positive hydrogen breath test for lactose intolerance is a biomarker of when an IBS patient could be successful treated with dietary therapy.

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Gastrointestinal Problems in Children with Autism

A recently published study from the University of California at Davis Health System shows that autistic children have eight times more gastrointestinal problems than other children. To reach this conclusion researchers studied almost 1000 young children. The stomach problems, which include constipation, diarrhea and sensitivity to food might be responsible for behavior issues in autistic children. The researchers concluded that more should be done to understand the causes of the stomach problems so that the children can be appropriately treated. Furthermore, the researchers believed that such treatment might improve behavior problems. Metabolic Solutions offers the hydrogen breath tests for fructose malabsorption and lactose intolerance that might be beneficial in understanding the stomach problems found in autistic kids.

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